I suppose it depends on how you define best and worst. I like some of these sandwiches very much. In terms of calories and saturated fats, the 10 Worst Sandwiches in America according to Men’s Health:
#10: Cosi Steak TBM (Tomatoes, Basil, Mozzarella) 829 calories
#9: Arby's Ultimate BLT Market Fresh Sandwich 880 calories
#8: Jimmy John's Italian Night Club 951 calories
#7: Panera Full Chipotle Chicken on Artisan French Bread 990 calories
#6. Red Robin Whiskey River BBQ Chicken Sandwich 1,112 calories
#5. Subway Meatball Marinara Footlong 1,160 calories
#4. Blimpie Special Vegetarian 12" 1,186 calories 
#3. Applebee's Grilled Cheese BLT 1,310 calories
#2. Quizno's Large Tuna Melt 1,760 calories
#1: The Worst Sandwich in America Cheesecake Factory Grilled Shrimp & Bacon Club 1930 calories